HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Difluorobenzoyl chloride → 4-[3-(3,4-Difluorobenzamidyl)benzoyl]-1-methylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Difluorobenzoyl chloride | HCID 2724519 | — |
| Reactant | 4-[3-Aminobenzoyl]-1-methylpiperidine | HCID 10130651 | — |
| Product | 4-[3-(3,4-Difluorobenzamidyl)benzoyl]-1-methylpiperidine | HCID 69355181 | — |
Reaction Steps
Beginning with 4-[3-aminobenzoyl]-1-methylpiperidine (25 mg, 0.115 mmol) and 3,4-difluorobenzoyl chloride (29 μL, 0.229 mmol) and mixing for 24 h, 45.6 mg (>100%) of the title compound were recovered.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777428B1 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-5aebbc0b16e5416b8d5b840b0151dea0 |
| Source note | uspto-grants-2004_08 |