Methyl isothiocyanate → HCID 86759511, compound

HRID 1836412Notes

Reaction equation

HRID 1836412 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[C:5]([CH:7]1[CH2:12][CH2:11][N:10]([CH3:13])[CH2:9][CH2:8]1)=[O:6].[CH3:17][N:18]=[C:19]=[S:20]>>[CH3:17][NH:18][C:19](=[S:20])[NH:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[C:5]([CH:7]1[CH2:8][CH2:9][N:10]([CH3:13])[CH2:11][CH2:12]1)=[O:6]

Participants

3

Reactant 2

HCID 11167Methyl isothiocyanateHCID 101306514-[3-Aminobenzoyl]-1-methylpiperidine

Product 1

HCID 86759511HCID 86759511, compoundYield 66%

Procedure

Following the example above and beginning with 4-[3-aminobenzoyl]-1-methylpiperidine (25 mg, 0.115 mmol) and methyl isothiocyanate (124 μL, 1.813 mmol), 22.0 mg (66%) of the title compound were recovered.

Sources & evidence

ORD record
ord-7da0bee5f7c8475988b2199aa830e197
Source dataset
uspto-grants-2004_08
Patent number
US06777428B1

Reaction notes

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