3,4-Dichlorobenzaldehyde → HCID 74058494, compound

Participants

Reaction Steps

Condensation of 3,4-dichlorobenzaldehyde with hydroxylamine hydrochloride followed by reaction with tert-butyl bromoacetate using a procedure similar to the one described for the preparation of compound 6-A gave the title oxime ether as a clear oil after chromatography on silica gel (elution dichloromethane-hexane 1:1) (94% yield). 1HNMR 400 MHz (CDCl3) δ (ppm): 1.52 (9H, s, t-Bu), 4.63 (2H, s, OCH2), 7.41 (1H, dd, J=1.9 Hz and J=8.6 Hz, aromatic), 7.47 (1H, d, J=8.6 Hz, aromatic), 7.71 (1H, d, J=1.9 Hz, aromatic), 8.13 (1H, s, CH).

Provenance & Evidence