Methanol → 1-Tert-butoxycarbonyl-3-azabicyclo[3.2.0]heptane

HRID 183663Notes

Reaction equation

HRID 183663 reaction equation
[C+4:29].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[C:8]12[CH2:9][N:10]([C:15]([O:16][CH2:17][c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)=[O:24])[CH2:11][CH:12]1[CH2:13][CH2:14]2.[CH3:27][OH:28].[H:25][H:26].[OH-:30].[OH-:32].[OH-:33].[OH-:34].[OH-:35].[OH-:36].[Pd+2:31]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[C:8]12[CH2:9][NH:10][CH2:11][CH:12]1[CH2:13][CH2:14]2

Participants

7

Reactant 6

HCID 887MethanolHCID 961Hydroxide6×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 221005281-Tert-butoxycarbonyl-3-benzyloxycarbonyl-3-azabicyclo[3.2.0]heptaneHCID 178418361HCID 178418361, compoundHCID 178420935HCID 178420935, compound

Product 1

HCID 221005211-Tert-butoxycarbonyl-3-azabicyclo[3.2.0]heptane

Sources & evidence

ORD record
ord-0f3eae92362c4b6ea78b7314abf0d1f8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…