HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 2-(3-thienyl)benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-Bromobenzaldehyde | HCID 81129 | — |
| Reactant | Thiophene-3-boronic acid | HCID 581760 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-(3-thienyl)benzaldehyde | HCID 4321315 | — |
Reaction Steps
The reaction was repeated on a 50 mmol scale with 2-bromobenzaldehyde (5.8 mL), thiophene-3-boronic acid (7.03 g, 0.0555 mol) in ethanol (55 mL), Pd(PPh3)4 (1.7 g, 3 mol %), 2 M aqueous Na2CO3 (55 mL) in toluene (275 mL) to yield crude 2-(3-thienyl)benzaldehyde as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777421B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-7778c2f78bb843feabed8eb6452c5c2a |
| Source note | uspto-grants-2004_08 |