2-(2-Methoxyphenoxy)ethyl amine → 1-(9-Benzenesulfonyl-9H-carbazol-4-yloxy)-3-{benzyl-[2-(2-methoxy-phenoxy)-ethyl]-amino}-propan-2-ol

HRID 1836706Notes

Reaction equation

HRID 1836706 reaction equation
[C:1]1([S:7]([N:10]2[C:22]3[CH:21]=[CH:20][CH:19]=[C:18]([O:23][CH2:24][CH:25]4[CH2:27][O:26]4)[C:17]=3[C:16]3[C:11]2=[CH:12][CH:13]=[CH:14][CH:15]=3)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:28][O:29][C:30]1[CH:39]=[CH:38][CH:37]=[CH:36][C:31]=1[O:32][CH2:33][CH2:34][NH2:35]>>[C:1]1([S:7]([N:10]2[C:22]3[CH:21]=[CH:20][CH:19]=[C:18]([O:23][CH2:24][CH:25]([OH:26])[CH2:27][N:35]([CH2:17][C:16]4[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=4)[CH2:34][CH2:33][O:32][C:31]4[CH:36]=[CH:37][CH:38]=[CH:39][C:30]=4[O:29][CH3:28])[C:17]=3[C:16]3[C:11]2=[CH:12][CH:13]=[CH:14][CH:15]=3)(=[O:8])=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 17130052-(2-Methoxyphenoxy)ethyl amineHCID 11234330HCID 11234330, compound

Product 1

HCID 114792061-(9-Benzenesulfonyl-9H-carbazol-4-yloxy)-3-{benzyl-[2-(2-methoxy-phenoxy)-ethyl]-amino}-propan-2-ol

Procedure

reaction of 9-benzenesulfonyl-4-oxiranylmethoxy-9H-carbazole with benzyl-[2-(2-methoxy-phenoxy]-ethyl-amine to give a 1-(9-benzenesulfonyl-9H-carbazol-4-yloxy)-3-{benzyl-[2-(2-methoxy-phenoxy)ethyl]-amino}-propan-2-ol;

Sources & evidence

ORD record
ord-d79fc1c8f319407c8d83321b9492e7a1
Source dataset
uspto-grants-2004_08
Patent number
US06777559B2

Reaction notes

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