Epichlorohydrin → 4-Oxiranylmethoxy-9H-carbazole

HRID 1836707Notes

Reaction equation

HRID 1836707 reaction equation
[OH:1][C:2]1[C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1.[CH2:15]([CH:17]1[O:19][CH2:18]1)Cl>>[O:19]1[CH2:18][CH:17]1[CH2:15][O:1][C:2]1[C:14]2[C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[NH:7][C:6]=2[CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 7835EpichlorohydrinHCID 1042514-Hydroxycarbazole2×

Product 1

HCID 50207104-Oxiranylmethoxy-9H-carbazole

Procedure

deprotection of 9-benzenesulfonyl-9H-carbazol-4-ol to give 4-hydroxy-carbazole reaction of 4-hydroxy-carbazole with epichlorohydrin under basic conditions to give 4-oxiranylmethoxy-9H-carbazole;

Sources & evidence

ORD record
ord-2942dfd1daf34aa59856cce9785fb8d6
Source dataset
uspto-grants-2004_08
Patent number
US06777559B2

Reaction notes

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