反应详情

温度

50 °C

A solution of 0.96 g of acetic acid 9-benzenesulfonyl-9H-carbazol-4-yl ester (2.62 mmol) in 15 ml of methanol was treated with 3.5 ml of 4 M sodium hydroxide (14 mmol) and stirred at 50° C. for 1.5 h. After cooling to room temperature, methanol was removed from the reaction mixture by rotary evaporation and the residue was partitioned between t-butyl methyl ether and 2N aq. HCl. After drying (Na2SO4) the organic phase was evaporated to dryness to afford 0.84 g (99%) of 9-benzenesulfonyl-9H-carbazol-4-ol as an orange brown oil.

1. temperatureAfter cooling to room temperature
2. custommethanol was removed from the reaction mixture by rotary evaporation
3. customthe residue was partitioned between t-butyl methyl ether and 2N aq. HCl
4. dry with materialAfter drying (Na2SO4) the organic phase
5. customwas evaporated to dryness