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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 183673Generated: October 26, 2026

Hydrochloric Acid → (RS)-N-(3,5-Difluoro-benzyl)-2-methyl-N'-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-malonamide

https://huagongshe.com/reaction/183673

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTetrahydrofuranHCID 8028—
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
ReactantDiisopropylethylamineHCID 81531—
Reactant3-Amino-1-methyl-5-phenyl-1H-benzo[E][1,4]diazepin-2(3H)-oneHCID 2729681—
ReactantN-(3,5-difluoro-benzyl)-2-methyl-malonamic acidHCID 21091473—
Product(RS)-N-(3,5-Difluoro-benzyl)-2-methyl-N'-(1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-malonamideHCID 10005794—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-87a31b976ca845799de86992f8ea9b5c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)