HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → HCID 178473177, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | 2-Thiazolemethanol, alpha-methyl- (7CI,9CI) | HCID 9989295 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 178473177 | HCID 178473177 | 78.8% |
Reaction Steps
A mixture of 1-(2-thiazolyl)ethanol (1.17 g, 8.67 mmole) and ethyl bromoacetate (1.32 g, 8.63 mmole) was heated at 48 C. for 18 hr. The reaction mixture was dissolved in acetonitrile (3 mL) and stored at 4 C. After 2 months the crystals which separated were filtered out and washed with 3:7 ether-acetonitrile to yield 2.028 g of the title compound, mp 101-103 C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777557B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-18318557348147dfa7f92c4c749e9a23 |
| Source note | uspto-grants-2004_08 |