Chloride → HCID 22220827, compound

Participants

Reaction Steps

1-[2-(1-Pyrrolidinyl)-2-oxoethyl]-2-(cyanomethyl)pyridinium bromide (0.74 g, 2.39 mmole) was dissolved in water (3 mL), loaded onto an Amberlite IRA-400 column (chloride form, 2.5 cm×19 cm) and eluted with distilled water. Fractions 1 (30 mL) and 2 (20 mL) were evaporated under reduced pressure and the residue was recrystalized from acetonitrile-ether to give the title compound as 0.512 g of prisms, mp 130-132° C. Calcd for C13H16N3OCl: C 58.70, H 6.02, N 15.80, Cl 13.34; found: C 58.68, H 6.24, N 15.88, Cl 13.31.3-(2-Oxo-2-phenylethyl)-2-(1-acetoxyethyl)thiazolium bromide

Provenance & Evidence