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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836785Generated: November 3, 2026

Ethanol → Ethyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoate

https://huagongshe.com/reaction/1836785

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthanolHCID 702—
Reactant2-(4-Cyclopropanecarbonyl-phenyl)-2-methylpropionamideHCID 23499851—
ProductEthyl 2-[4-(cyclopropanecarbonyl)phenyl]-2-methylpropanoateHCID 9813859—

Reaction Steps

Dissolve 2-(4-cyclopropanecarbonyl-phenyl)-2-methyl-propionamide (100 mg) in ethanol and bubble in hydrochloride gas for 5 minutes while stirring. Reflux for 10 hours, distill off the ethanol and extract into ethyl acetate. Evaporate the solvent in vacuo to give the title compound as an oil (50 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777555B2
Source datasetuspto-grants-2004_08
ORD IDord-d1927407845649e98c016f21570be2d7
Source noteuspto-grants-2004_08