4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromide → 2-Benzyl-7-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl]piperazin-1-yl]-3,4-dihydro-2H-isoquinolin-1-one

Participants

Role	Name	HCID	Charge
Reactant	4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromide	HCID 22180203	—
Reactant	2-Benzyl-7-(4-t-butoxycarbonyl-piperazin-1-yl)-3,4-dihydro-2H-isoquinolin-1-one	HCID 22180449	—
Product	2-Benzyl-7-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl]piperazin-1-yl]-3,4-dihydro-2H-isoquinolin-1-one	HCID 22180217	—

Reaction Steps

Step (b) of Example 97 was repeated, except that the compound prepared in step (a) of Example 97 and the compound prepared in step (a) of Example 96 were used. Thus, the title compound was prepared.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06777414B1
Source dataset	uspto-grants-2004_08
ORD ID	ord-cab236d3bcaf4f31a4463eed5b0db3b9
Source note	uspto-grants-2004_08