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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836830Generated: October 25, 2026

N-Allylcyclohexylamine → N-Allyl-N-cyclohexyl-2-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-5-methylisonicotinamide

https://huagongshe.com/reaction/1836830

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-AllylcyclohexylamineHCID 81115—
Reactant2-[4-(3,3-Diphenyl-1-propyl)piperazin-1-yl]-5-methylisonicotinic acidHCID 22180640—
ProductN-Allyl-N-cyclohexyl-2-[4-(3,3-diphenyl-1-propyl)piperazin-1-yl]-5-methylisonicotinamideHCID 2218051172.8%

Reaction Steps

Step (d) of Example 107 was repeated, except that the compound (50 mg) prepared in step (d) of Example 108 and allylcyclohexylamine (34 mg) were used as the starting compounds. Thus, the title compound (47 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777414B1
Source datasetuspto-grants-2004_08
ORD IDord-33980045cf3f4ea698aec39c0545e2df
Source noteuspto-grants-2004_08