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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836842Generated: October 27, 2026

2-benzyl-7-piperazinyl-2H-phthalazin-1-one → 2-Benzyl-7-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]-piperazin-1-yl]-2H-phthalazin-1-one

https://huagongshe.com/reaction/1836842

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-benzyl-7-piperazinyl-2H-phthalazin-1-oneHCID 22180278—
Reactant3-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl bromideHCID 22180583—
Product2-Benzyl-7-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]-piperazin-1-yl]-2H-phthalazin-1-oneHCID 22180174—

Reaction Steps

Step (c) of Example 92 was repeated, except that the compound prepared in step (b) of Example 114 and the compound prepared in step (e) of Example 137 were used as the starting compounds. Thus, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777414B1
Source datasetuspto-grants-2004_08
ORD IDord-e3101a2ea8c74afe8a25aa288cc4235d
Source noteuspto-grants-2004_08