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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836845Generated: October 31, 2026

7-piperazinyl-2-(pyridin-2-yl)methyl-2H-phthalazin-1-one → 2-(Pyridin-2-yl)methyl-7-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]-2H-phthalazin-1-one

https://huagongshe.com/reaction/1836845

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-piperazinyl-2-(pyridin-2-yl)methyl-2H-phthalazin-1-oneHCID 22180293—
Reactant3-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl bromideHCID 22180583—
Product2-(Pyridin-2-yl)methyl-7-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]-2H-phthalazin-1-oneHCID 22180455—

Reaction Steps

Step (b) of Example 92 was repeated, except that the compound prepared in step (b) of Example 114 and the compound prepared in step (c) of Example 143 were used as the starting compounds. Thus, the title compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777414B1
Source datasetuspto-grants-2004_08
ORD IDord-a40d9e1625fd4ebcb16a1195d112489d
Source noteuspto-grants-2004_08