1,1'-(3-Bromopropylidene)bisbenzene → 2-Benzyl-7-[4-(3,3-diphenylpropyl)piperazin-1-yl]-2H-phthalazin-1-one

HRID 1836847Notes

Reaction equation

HRID 1836847 reaction equation
[CH2:1]([N:8]1[N:17]=[CH:16][C:15]2[C:10](=[CH:11][C:12]([N:18]3[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]3)=[CH:13][CH:14]=2)[C:9]1=[O:24])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:25]1([CH:31]([C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[CH2:32][CH2:33]Br)[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[CH2:1]([N:8]1[N:17]=[CH:16][C:15]2[C:10](=[CH:11][C:12]([N:18]3[CH2:19][CH2:20][N:21]([CH2:33][CH2:32][CH:31]([C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=4)[C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=4)[CH2:22][CH2:23]3)=[CH:13][CH:14]=2)[C:9]1=[O:24])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 883331,1'-(3-Bromopropylidene)bisbenzeneHCID 221802782-benzyl-7-piperazinyl-2H-phthalazin-1-one

Product 1

HCID 221803302-Benzyl-7-[4-(3,3-diphenylpropyl)piperazin-1-yl]-2H-phthalazin-1-one

Procedure

The title compound was prepared using the compound prepared in step (e) of Example 137 and 3,3-diphenylpropyl bromide as starting compounds according to the method described in WO 9854135.

Sources & evidence

ORD record
ord-58c4522b32a9492e945cca3746f343ac
Source dataset
uspto-grants-2004_08
Patent number
US06777414B1

Reaction notes

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