HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-(piperazin-1-yl)benzoate → ethyl 4-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-fluoren-9-yl]propyl]piperazin-1-yl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-(piperazin-1-yl)benzoate | HCID 2761178 | — |
| Reactant | 3-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-fluoren-9-yl]propyl bromide | HCID 10597759 | — |
| Product | ethyl 4-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-fluoren-9-yl]propyl]piperazin-1-yl]benzoate | HCID 22180539 | — |
Reaction Steps
Step (b) of Example 1 was repeated, except that the compound prepared in step (a) of Example 80 and the compound prepared in step (a) of Example 93 were used as the starting compounds. Thus, ethyl 4-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-fluoren-9-yl]propyl]piperazin-1-yl]benzoate was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06777414B1 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-bd4657c468c545cb812c4c5e21b72a73 |
| Source note | uspto-grants-2004_08 |