Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836850Generated: November 3, 2026

Ethyl 4-(piperazin-1-yl)benzoate → HCID 22180424, compound

https://huagongshe.com/reaction/1836850

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 4-(piperazin-1-yl)benzoateHCID 2761178—
Reactant9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamideHCID 10526437—
ProductHCID 22180424HCID 22180424—

Reaction Steps

Step (b) of Example 1 was repeated, except that the compound prepared in step (a) of Example 80 was used as the starting compound and 4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-fluoren-9-yl]butyl bromide was used instead of 3,3-diphenyl bromide. Thus, ethyl 4-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-fluoren-9-yl]butyl]piperazin-1-yl]benzoate was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777414B1
Source datasetuspto-grants-2004_08
ORD IDord-37f19113aa3745748e0fbd0bdf8ed0fe
Source noteuspto-grants-2004_08