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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836851Generated: November 3, 2026

3-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl bromide → ethyl 2-methyl-3-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]benzoate

https://huagongshe.com/reaction/1836851

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl bromideHCID 22180583—
ReactantEthyl 2-methyl-3-piperazin-1-ylbenzoateHCID 22180591—
Productethyl 2-methyl-3-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]benzoateHCID 22180646—

Reaction Steps

Step (b) of Example 1 was repeated, except that the compound prepared in step (a) of Example 53 and the compound prepared in step (b) of Example 114 were used as the starting compounds. Thus, ethyl 2-methyl-3-[4-[3-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]propyl]piperazin-1-yl]benzoate was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777414B1
Source datasetuspto-grants-2004_08
ORD IDord-4caab5139f754715bcc12ae10b80a60a
Source noteuspto-grants-2004_08