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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1836857Generated: November 1, 2026

4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromide → ethyl 2-methyly-3-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl]piperazin-1-yl]benzoate

https://huagongshe.com/reaction/1836857

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromideHCID 22180203—
ReactantEthyl 2-methyl-3-piperazin-1-ylbenzoateHCID 22180591—
Productethyl 2-methyly-3-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl]piperazin-1-yl]benzoateHCID 86594988—

Reaction Steps

The procedure of step (b) of Example 1 was repeated, except that the compound prepared in step (a) of Example 53 and the compound prepared in step (a) of Example 96 were used as the starting compounds. Thus, ethyl 2-methyly-3-[4-[4-[9-(2,2,2-trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl]piperazin-1-yl]benzoate was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06777414B1
Source datasetuspto-grants-2004_08
ORD IDord-eec63ed0e63b47129101d3f927f4835a
Source noteuspto-grants-2004_08