Formaldehyde → HCID 69677328, compound

Participants

Reaction Conditions

Reaction Steps

A one liter flask was charged with 301.2 g phenol (3.2 moles) and 194 g. N-ethylaniline (1.6 moles). The reaction mixture was heated to 70° C. and then 192 g 50% formalin (3.2 moles) was added over 45 minutes at 70-72° C. After 1½ hours at 71-73° C., 4 g acetic acid was added. The temperature was raised to 80° C. and maintained at 80° C. for 2 hours. The temperature was raised to 100° C. and maintained for 1½ hour. Reaction mixture was then atmospherically distilled to 160° C. to collect 156 g distillate. Phenol (92.1 g) was then recovered by vacuum distillation increasing temperature to 190° C. while increasing vacuum to 30 inches of mercury. Product yield was 432.7 g and is characterized in Table 1B.

Provenance & Evidence