Formaldehyde → HCID 69677332, compound

Participants

Reaction Conditions

Reaction Steps

A one liter flask was charged with 376.4 g phenol (4.0 moles), 171.5 g N-methylaniline (1.6 moles) and 7.0 g 90% formic acid. The reaction mixture was heated to 70° C. and then 191 g 50% formalin (3.2 moles) was added at 70° C. over 1 hour. The temperature was maintained at 70° C. for 2 hours at which time the percent free phenol was determined to be 34.8% (vs. 50.5% for no reaction of phenol). The temperature was raised to 100° C. and maintained at 100° C. for one hour at which time the percent free phenol was 33.6%. Reaction mixture was then atmospherically distilled to 160° C. to collect 163 g distillate. Phenol (170 g) was then recovered by vacuum distillation increasing temperature to 190° C. while increasing vacuum to 30 inches of mercury. Product yield was 397 g and is characterized in Table 2B and Table 5.

Provenance & Evidence