HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclopentanedione → 4-(3-Iodo-4-methylphenyl)-1-methyl-1,2,4,6,7,8-hexahydrocyclopenta[b]pyrazolo[4,3-e]pyridine-3,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclopentanedione | HCID 77466 | — |
| Reactant | 5-amino-1-methyl-2,3-dihydro-1H-pyrazol-3-one | HCID 252198 | — |
| Reactant | 3-Iodo-4-methylbenzaldehyde | HCID 12330254 | — |
| Product | 4-(3-Iodo-4-methylphenyl)-1-methyl-1,2,4,6,7,8-hexahydrocyclopenta[b]pyrazolo[4,3-e]pyridine-3,5-dione | HCID 10112893 | 23.7% |
Reaction Steps
3-Iodo-4-methylbenzaldehyde (0.37 g, 1.5 mmol) from Example 11A, 1,3-cyclopentadione (0.15 g, 1.5 mmol), and 5-amino-1-methyl-1,2-dihydropyrazol-3-one (0.17 g, 1.5 mmol) were processed as described in Example 1 to provide 0.15 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06780872B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-122db1262b244c2c9f52d69e88dc1da5 |
| Source note | uspto-grants-2004_08 |