HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Butyn-2-ol → Methyl [(1-methyl-2-propynyl)oxy]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Butyn-2-ol | HCID 16239 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Product | Methyl [(1-methyl-2-propynyl)oxy]acetate | HCID 18619750 | — |
Reaction Steps
Sodium hydride (60% dispersion in mineral oil, 10 g, 0.25 mol), (±)-3-butyn-2-ol (21 g, 0.30 mol), and methyl bromoacetate were processed as described in Example 43A to provide the title compound. 1H NMR (CDCl3) δ 1.51 (d, 3H), 2.46 (d, 1H), 3.76 (s, 3H), 4.25 (AB q, 2H), 4.39 (dq, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06780872B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-ad9bda268a0a42f0ab708ff0d326f671 |
| Source note | uspto-grants-2004_08 |