HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitro-n-[1-(4-pyridyl)piperidin-4-ylmethyl]pyridine-2-amine → N2-[1-(4-pyridyl)piperidin-4-ylmethyl]-2,3-pyridinediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitro-n-[1-(4-pyridyl)piperidin-4-ylmethyl]pyridine-2-amine | HCID 23497755 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Product | N2-[1-(4-pyridyl)piperidin-4-ylmethyl]-2,3-pyridinediamine | HCID 12150690 | 97.1% |
Reaction Steps
Using a similar procedure to that described in Example 2, Part C, 3-nitro-N-[1-(4-pyridyl)piperidin-4-ylmethyl]pyridine-2-amine (340 mg, 1.09 mmol) and 10% palladium on carbon (200 mg) yielded 300 mg of the title compound, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06780878B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-ccb283b927fa4a61b469cf6c1972a9a0 |
| Source note | uspto-grants-2004_08 |