HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Anisoyl chloride → N3-(4-Methoxybenzoyl)-N4-[1-(4-pyridyl)-piperidin-4-ylmethyl]-3,4-pyridinediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Anisoyl chloride | HCID 7477 | — |
| Reactant | N4-[1-(4-pyridyl)piperidin-4-ylmethyl]-3,4-pyridinediamine | HCID 70034615 | — |
| Product | N3-(4-Methoxybenzoyl)-N4-[1-(4-pyridyl)-piperidin-4-ylmethyl]-3,4-pyridinediamine | HCID 9955571 | 6.2% |
Reaction Steps
Using a similar procedure to that described in Example 2, Part D, N4-[1-(4-pyridyl)piperidin-4-ylmethyl]-3,4-pyridinediamine (110 mg, 0.388 mmol) and 4-methoxybenzoyl chloride (0.66 mL, 0.388 mmol) yielded 10 mg (6%) of the title compound as a hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06780878B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-24ac4edecb384d79af6dcaf41c14bbc5 |
| Source note | uspto-grants-2004_08 |