HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4,5,6-Trichloropicolinoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Pyridinecarboxylic acid, 4,5,6-trichloro- | HCID 12993692 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Product | 4,5,6-Trichloropicolinoyl chloride | HCID 12993693 | — |
Reaction Steps
A solution of 4,5,6-trichloropyridine-2-carboxylic acid (5.20 g, 23.1 mmol) and thionyl chloride (3.0 mL) in dichloroethane (30 mL) was refluxed until the evolved gas ceased. The reaction mixture was concentrated to give 4,5,6-trichloropyridine-2-carbonyl chloride (5.60 g, 23.0 mmol), mp 60-62° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06784137B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-d44e9346ba8e4160826637104e603b28 |
| Source note | uspto-grants-2004_08 |