Chloral → HCID 15541327, compound

HRID 1837498Notes

Reaction equation

HRID 1837498 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]1.ClC(Cl)(Cl)[CH:16]=[O:17]>C(OCCCC)CCC>[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH2:13][CH2:12][N:11]([CH:16]=[O:17])[CH2:10][CH2:9]1

Participants

4

Reactant 2

HCID 6407ChloralHCID 919652-Mepp

Product 1

HCID 15541327HCID 15541327, compound

Reagents, catalysts & solvents 1

HCID 8909Butyl etherSolvent

Conditions

Temperature
80 °C

Procedure

With vigorous stirring, 437 mmol (77 g) of 2-methylphenylpiperazine are added to a solution of 415 mmol (61.3 g) of trichloroacetaldehyde in 400 ml of dibutyl ether. The reaction mixture is heated at 80° C. for 1 hour and, after cooling, concentrated to yield the expected product.

Workup

  1. temperatureafter cooling
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-fad46f1dd699494eb2721a472b6a2eb3
Source dataset
uspto-grants-2004_08
Patent number
US06784183B2

Reaction notes

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