HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 6-nitro-3,4-dihydro-2H-1-benzopyran-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Chromanone | HCID 68110 | — |
| Product | 6-nitro-3,4-dihydro-2H-1-benzopyran-4-one | HCID 5228831 | — |
Reaction Steps
At −35° C., 60 g of 4-chromanone are added in small portions to 385 ml of 90% nitric acid. The whole is poured onto ice and then extracted with dichloromethane. The organic phase is washed with a saturated solution of sodium hydrogen carbonate and dried over magnesium sulphate and then the solvent is evaporated off.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06784183B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-21bfbad5cb344a3da004b3f1bf9f0d8f |
| Source note | uspto-grants-2004_08 |