Propyl Isothiocyanate → HCID 10386171, compound

Participants

Reaction Steps

Using the general method of Example 150, 1-(3-aminopropyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine (1.5 g, 5.04 mmol) was reacted with propyl isothiocyanate (560 mg, 5.55 mmol) to provide 1.34 g of N-[3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]-N′-propylthiourea as a crystalline solid, m.p. 144.5-145.5° C. Analysis: Calculated for C21H30N6S. 0.56H2O: %C, 61.72; %H, 7.68; %N, 20.56; Found: %C, 61.72; %H, 7.67; %N, 20.56.

Provenance & Evidence