Phenyl isocyanate → HCID 10368159, compound

Participants

Reaction Steps

Using the general method of Example 145, 1-(8-aminooctyl)2-butyl-1H-imidazo[4,5-c]quinolin-4amine (1.2 g, 3.26 mmol) was reacted with phenyl isocyanate to provide 1.59 g of N-[8-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)octyl]-N′-phenylurea as an off white powder, m.p. 153-155° C. Analysis: Calculated for C29H38N6O. 0.20H2O: %C, 71.05; %H, 7.89; %N, 17.14; Found: %C, 70.86; %H, 7.97; %N, 16.87.

Provenance & Evidence