Phenyl isocyanate → HCID 10095008, compound

Participants

Reaction Steps

Using the general method of Example 149, 1-(4aminobutyl)-2-pentyl-1H-imidazo[4,5-c]quinolin-4-amine (800 mg, 2.5 mmol) was reacted with phenyl isocyanate (0.26 mL, 2.5 mmol) to provide 299 mg of N-[4-(4-amino-2-pentyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]-N′-phenylurea as an off white solid, m.p. 159.0-160.4° C. Analysis: Calculated for C26H32N6O2. 1.0H2O: %C, 67.5 1; %H, 7.4 1; %N, 18.17; Found: %C, 67.73; %H, 7.33; %N, 17.97.

Provenance & Evidence