1-[(2-Methoxy-3-pyridinyl)methyl]-4-[(E)-2-(2-methylphenyl)-1-ethenyl]piperidine → 1-[(2-Methoxy-3-pyridinyl)methyl]-4-[2-(2-methylphenyl)ethyl]piperidine

Participants

Reaction Steps

In ethanol (10 ml) was dissolved 473 mg of 1-[(2-methoxy-3-pyridinyl)methyl]-4-[(E)-2-(2-methylphenyl)-1-ethenyl]piperidine. To the mixture was added 100 mg of 10% palladium-carbon powder (water-containing product) was added thereto, followed by stirring at room temperature under normal pressure overnight in a hydrogen atmosphere for 1.5 hours. The reaction solution was filtered, and then the filtrate was evaporated, to give 465 mg of the title compound as a colorless oil.

Provenance & Evidence