Tetrabutylammonium → Tert-butyl 2-(fluoromethyl)azetidine-1-carboxylate

HRID 183781Notes

Reaction equation

HRID 183781 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:12][O:13][S:14]([CH3:15])(=[O:16])=[O:17])[CH2:10][CH2:11]1.[CH3:19][CH2:20][CH2:21][CH2:22][N+:23]([CH2:24][CH2:25][CH2:26][CH3:27])([CH2:28][CH2:29][CH2:30][CH3:31])[CH2:32][CH2:33][CH2:34][CH3:35].[F-:18]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:12][F:18])[CH2:10][CH2:11]1

Participants

4

Reactant 3

HCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 72272967Tert-butyl 2-((methanesulfonyloxy)methyl)azetidine-1-carboxylate

Product 1

HCID 66701899Tert-butyl 2-(fluoromethyl)azetidine-1-carboxylate

Sources & evidence

ORD record
ord-ff6587af56194b588d2ccad5b2553340
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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