HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1837870Generated: November 1, 2026
Hydrochloric Acid → 5-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)pentanoic acid hydrochloride
https://huagongshe.com/reaction/1837870
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl 5-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)pentanoate | HCID 11265157 | — |
| Product | 5-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)pentanoic acid hydrochloride | HCID 69775059 | — |
Reaction Steps
A mixture of 1-5 (620 mg, 2.50 mmol) and 6N HCl (12 mL) was heated at 50° C. for 18 h. Evaporative removal of the solvent gave 1-6 as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06784190B2 |
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| Source dataset | uspto-grants-2004_08 |
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| ORD ID | ord-5c53e7267e474a08945f4bd12f3bd7c5 |
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| Source note | uspto-grants-2004_08 |
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