HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5,6,7,8-Tetrahydro-1,8-naphthyridin-2-butyric acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Ethyl 4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)butanoate | HCID 22594332 | — |
| Product | 5,6,7,8-Tetrahydro-1,8-naphthyridin-2-butyric acid hydrochloride | HCID 69776037 | — |
Reaction Steps
Ester 2-4 (1.8 g, 7.25 mmol) in 36 mL 6 N HCl was heated at 50° C. for 4 h, then concentrated, providing 2-5 as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06784190B2 |
| Source dataset | uspto-grants-2004_08 |
| ORD ID | ord-9bcbd9d6c65c439889eb9b922c4c3bc8 |
| Source note | uspto-grants-2004_08 |