N-Benzyl-2-chloroacetamide → 2-[(2-Amino-5-chloro-3-pyridinyl)oxy]-N-benzylacetamide

HRID 1838081노트

반응식

HRID 1838081 반응식
[NH2:1][C:2]1[C:7]([OH:8])=[CH:6][C:5]([Cl:9])=[CH:4][N:3]=1.[CH2:10]([NH:17][C:18](=[O:21])[CH2:19]Cl)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[NH2:1][C:2]1[C:7]([O:8][CH2:19][C:18]([NH:17][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:21])=[CH:6][C:5]([Cl:9])=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 96233N-Benzyl-2-chloroacetamideHCID 103132002-Amino-5-chloropyridin-3-ol

생성물 1

HCID 185116922-[(2-Amino-5-chloro-3-pyridinyl)oxy]-N-benzylacetamide

실험 절차

The title compound was prepared by the method of P. Nedenskov, N. Clauson-Kaas, J. Lei, H.-N. Heide, G. Olsen and G. Jansen (Acta Chemica Scandinavica, 1969, 23, 1791) from 2-amino-5-chloro-3-pyridinol (G. Mattern, Helv. Chimica Acta, 1977, 60, 2062) and N-benzyl-α-chloroacetamide. Sand coloured solid:

출처 및 근거

ORD 기록
ord-a6ae86f32e7d4fbea202b14de4d9ae9d
출처 데이터셋
uspto-grants-2004_01
특허 번호
US06673789B2

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