HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → Methyl 3-(bromomethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 3-Methylbenzoic acid | HCID 7418 | — |
| Reactant | Benzoic acid, 3-methyl-, methyl ester | HCID 7435 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 3-(bromomethyl)benzoate | HCID 517981 | — |
Reaction Steps
This is prepared as follows: 3-Toluic acid is converted with methanol in the presence of sulfuric acid into 3-toluic acid methyl ester, which reacts with N-bromosuccinimide to give 3-bromomethyl-benzoic acid methyl ester. Reaction of bromomethyl-benzoic acid methyl ester with triphenylphosphane finally leads to 3-(benzoic acid methyl ester)-methyltriphenylphosphonium bromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06673794B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-340eac9a63fc461b8cf4403c0b636380 |
| Source note | uspto-grants-2004_01 |