反应详情

4-(2-Amino-2-methylpropylamino)-2-trifluoromethylbenzonitrile was dissolved in 60 ml of dichloromethane, 0.49 ml of 4-fluorophenyl isocyanate was added dropwise to the solution and then the mixture was stirred at room temperature for 1 hour. The thus precipitated crystals were collected by filtration, washed with dichloromethane and then dried to obtain 1.30 g of the title compound.

1. filtrationThe thus precipitated crystals were collected by filtration
2. washwashed with dichloromethane
3. customdried