HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzhydrylpiperazine → HCID 10227913, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzhydrylpiperazine | HCID 70048 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | HCID 18753383 | HCID 18753383 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10227913 | HCID 10227913 | 53.4% |
Reaction Steps
3-[3-(3-nitrophenyl)-4,5-Dihydroisoxazol-5-yl]propanal (21.9 mg, 0.088 mmol), 1-(diphenylmethyl)piperazine (20.3 mg, 0.080 mmol), molecular sieves (5 beads), and NaBH(OAc)3 (51.1 mg, 0.241 mmol) were reacted in 3 mL of methylene chloride for about 12 hr. With the following processes the same as in Example 1, 20.7 mg (48.4%) of the target compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06673800B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-d38e7a4d5c15406eb683d3d2b70a966b |
| Source note | uspto-grants-2004_01 |