Diisopropylethylamine → HCID 18753390, compound

Participants

Reaction Steps

3-[3-(3-Nitrophenyl)-4,5-dihydroisoxazol-5-yl] propanal (23.8 mg, 0.096 mmol), 1-(2-methoxyphenyl)piperazine hydrochloride (20.0 mg, 0.087 mmol), molecular sieve (5 beads), NaBH(OAc)3 (55.5 mg, 0.262 mmol) and diisopropylethylamine. (26.9 L, 0.087 mmol) were reacted in 3 mL of methylene chloride for about 12 hr. With the following processes the same as in Example 1, 31.2 mg (78.6%) of the target compound was obtained.

Provenance & Evidence