1-(4-Fluorophenyl)piperazine → HCID 10298211, compound

Participants

Reaction Steps

3-(3-(2-Phenoxyphenyl)-4,5-dihydroisoxazol-5-yl)propanal (38.0 mg, 0.122 mmol), 1-(4-fluorophenyl)piperazine (20.0 mg, 0.111 mmol), molecular sieve (5 beads) and NaBH(OAc)3 (70.5 mg, 0.333mmol) were reacted in 3 mL of methylene chloride for about 12 hr. With the following processes the same as in Example 1, 28.7 mg (56.3%) of the target compound was obtained.

Provenance & Evidence