Benzhydrylpiperazine → HCID 10207100, compound

Participants

Reaction Steps

4-[3-(3-Nitrophenyl)-4,5-dihydroisoxazol-5-yl]butanal (30.0 mg, 0.114 mmol), 1-(diphenylmethyl)piperazine (26.2 mg, 0.104 mmol), molecular sieve (5 beads) and NaBH(OAc)3 (66.1 mg, 0.312 mmol) were reacted in 3 mL of methylene chloride 3 mL for about 12 hr. With the following processes the same as in Example 1, 28.4. mg (54.8%) of the target compound was obtained.

Provenance & Evidence