HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → HCID 10109334, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 4-(3-Phenyl-4,5-dihydroisoxazol-5-yl)butanal | HCID 18753392 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10109334 | HCID 10109334 | 79.8% |
Reaction Steps
4-(3-Phenyl-4,5-dihydroisoxazol-5-yl)butanal (29.4 mg, 0.135 mmol), 1-phenylpiperazine (20.0 mg, 0.123 mmol), molecular sieve (5 beads) and NaBH(OAc)3 (78.4 mg, 0.369 mmol) were reacted in 3 mL of methylene chloride for about 12 hr. With the following processes the same as in Example 1, 35.7 mg (68.4%) of the target compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06673800B2 |
| Source dataset | uspto-grants-2004_01 |
| ORD ID | ord-16a7bcbfa0e947cfbe085b8178b122cb |
| Source note | uspto-grants-2004_01 |