4-Methoxybenzenesulfonyl chloride → HCID 20610877, compound

HRID 1838425Notes

Reaction equation

HRID 1838425 reaction equation
[CH3:1][O:2][C:3](=[O:9])[C@H:4]([CH:6]([CH3:8])[CH3:7])[NH2:5].[CH3:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([S:18](Cl)(=[O:20])=[O:19])=[CH:14][CH:13]=1>>[CH3:1][O:2][C:3](=[O:9])[C@H:4]([CH:6]([CH3:8])[CH3:7])[NH:5][S:18]([C:15]1[CH:14]=[CH:13][C:12]([O:11][CH3:10])=[CH:17][CH:16]=1)(=[O:20])=[O:19]

Participants

3

Reactant 2

HCID 74014-Methoxybenzenesulfonyl chlorideHCID 94285Valine methyl ester

Product 1

HCID 20610877HCID 20610877, compoundYield 90%

Procedure

In a similar manner to that in Example 1(2)-b, a reaction was carried out using (±)-valine methyl ester and 4-methoxybenzenesulfonyl chloride to afford the desired compound (yield 90%) as a white powder.

Sources & evidence

ORD record
ord-c5f07fc94161464d8634112f2385363a
Source dataset
uspto-grants-2004_01
Patent number
US06673804B1

Reaction notes

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