Propanal → HCID 10599293, compound

HRID 1838480Notes

Reaction equation

[NH2:1][C:2]1[CH:7]=[C:6]([CH2:8][CH:9]([CH3:11])[CH3:10])[CH:5]=[CH:4][C:3]=1[C:12]1[C:13]([S:18]([NH:21][C:22]2[O:26][N:25]=[C:24]([CH3:27])[C:23]=2[CH3:28])(=[O:20])=[O:19])=[CH:14][CH:15]=[CH:16][CH:17]=1.[CH:29](=O)[CH2:30][CH3:31]>>[CH3:27][C:24]1[C:23]([CH3:28])=[C:22]([NH:21][S:18]([C:13]2[C:12]([C:3]3[CH:4]=[CH:5][C:6]([CH2:8][CH:9]([CH3:11])[CH3:10])=[CH:7][C:2]=3[NH:1][CH2:29][CH2:30][CH3:31])=[CH:17][CH:16]=[CH:15][CH:14]=2)(=[O:20])=[O:19])[O:26][N:25]=1

Participants

Reactant 2

HCID 527Propanal

HCID 9908909153624-15-8

Product 1

HCID 10599293HCID 10599293, compound

Conditions

Temperature: 2.5 °C

Procedure

The title compound was prepared from the compound of Example 32 and propionaldehyde as described for Example 58, with stirring at 0-5° C. for 2 hours. Following workup, chromatography on silica gel with 4:1 hexanes/ethyl acetate afforded the title compound as a light yellow gum.

Sources & evidence

ORD record: ord-9481ad17b581454e917994e104843cc6
Source dataset: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06673824B1

Reaction notes

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