Succinic anhydride → HCID 86585086, compound

HRID 1838521Notes

Reaction equation

[CH2:1]([OH:7])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[CH3:6].[C:8]1(=[O:14])[O:13][C:11](=[O:12])[CH2:10][CH2:9]1>>[C:8]([OH:13])(=[O:14])[CH2:9][CH2:10][C:11]([OH:7])=[O:12].[CH2:1]([OH:7])/[CH:2]=[CH:3]/[CH:4]=[CH:5]/[CH3:6]

Participants

Reactant 2

HCID 7922Succinic anhydride

HCID 641256(2E,4E)-Hexa-2,4-dien-1-ol

Product 1

HCID 86585086HCID 86585086, compound

Procedure

Trans,trans-hexa-2,4-dien-1-ol and succinic anhydride are reacted in the presence of N,N-dimethylaminopyridine to provide trans,trans-hexa-2,4-dien-1-ol monosuccinate. An aqueous solution of an excess of the monosuccinate is activated with 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide and coupled with human serum albumin, to provide a poly(diene) derivative 11.

Sources & evidence

ORD record: ord-2803042c6de24c4b8cf9111f06875d1c
Source dataset: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06673905B2

Reaction notes

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