(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate → N-cyclopropyl-4-methyl-3-[3-[[1-[2-(oxiran-2-ylmethoxy)phenyl]cyclopropyl]amino]-2-oxopyrazin-1-yl]benzamide

HRID 183855Notes

Reaction equation

HRID 183855 reaction equation
[CH:1]1([NH:4][C:5]([c:6]2[cH:7][c:8](-[n:13]3[c:14](=[O:30])[c:15]([NH:19][C:20]4([c:23]5[c:24]([OH:29])[cH:25][cH:26][cH:27][cH:28]5)[CH2:21][CH2:22]4)[n:16][cH:17][cH:18]3)[c:9]([CH3:12])[cH:10][cH:11]2)=[O:31])[CH2:2][CH2:3]1.[N+:32]([c:33]1[cH:34][c:35]([S:36]([O:37][CH2:45][CH:46]2[O:47][CH2:48]2)(=[O:38])=[O:39])[cH:40][cH:41][cH:42]1)([O-:43])=[O:44]>>[CH:1]1([NH:4][C:5]([c:6]2[cH:7][c:8](-[n:13]3[c:14](=[O:30])[c:15]([NH:19][C:20]4([c:23]5[c:24]([O:29][CH2:45][CH:46]6[O:47][CH2:48]6)[cH:25][cH:26][cH:27][cH:28]5)[CH2:21][CH2:22]4)[n:16][cH:17][cH:18]3)[c:9]([CH3:12])[cH:10][cH:11]2)=[O:31])[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 286836(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonateHCID 66688774N-Cyclopropyl-3-(3-(1-(2-hydroxyphenyl)cyclopropylamino)-2-oxopyrazin-1(2H)-yl)-4-methylbenzamide

Product 1

HCID 87109409N-cyclopropyl-4-methyl-3-[3-[[1-[2-(oxiran-2-ylmethoxy)phenyl]cyclopropyl]amino]-2-oxopyrazin-1-yl]benzamide

Sources & evidence

ORD record
ord-5f8cc7f792874415b8cee1e08301fcd3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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