Sodium Cyanide → HCID 69556852, compound

HRID 1838653Notes

Reaction equation

HRID 1838653 reaction equation
[S:1]([CH2:11][N+:12]#[C-:13])([C:4]1[CH:10]=[CH:9][C:7]([CH3:8])=[CH:6][CH:5]=1)(=[O:3])=[O:2].[CH3:14][S:15][C:16]1[CH:23]=[CH:22][C:19]([CH:20]=[O:21])=[CH:18][CH:17]=1.[C-]#N.[Na+]>>[CH3:14][S:15][C:16]1[CH:23]=[CH:22][C:19]([C@@H:20]2[O:21][CH:13]=[N:12][C@@H:11]2[S:1]([C:4]2[CH:10]=[CH:9][C:7]([CH3:8])=[CH:6][CH:5]=2)(=[O:3])=[O:2])=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 8929Sodium CyanideHCID 769854-(Methylthio)benzaldehydeHCID 161915Tosylmethyl isocyanide

Product 1

HCID 69556852HCID 69556852, compound

Procedure

In a manner analogous to Preparation 1, tosylmethylisocyanide (0.23 g, 1.20 mmol), 4-(methylthio)benzaldehyde (0.19 g, 1.26 mmol), and NaCN (5.9 mg, 0.12 mmol) gave the desired compound as a tan solid. MS(ES+) m/z 348.4 (M+H+).

Sources & evidence

ORD record
ord-05fd37cab0194f919b68cf53d3a6ab6d
Source dataset
uspto-grants-2004_01
Patent number
US06673941B2

Reaction notes

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